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Uses and side effects of brimonidine eye drops



Brimonidine is an eye drop for the eyes. Medical experts usually prescribe this eye drop for the treatment of open-angle glaucoma. So how does this medicine work and what are its side effects?

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The active ingredient of brimonidine is used to reduce intraocular pressure (IOP). Therefore, medical experts recommend using brimonidine eye drops for the treatment of high pressure and open glaucoma. In this article, we will discuss the use of this brimonidine eye drop and its side effects.

Glaucoma is a major risk factor for high pressure, which can cause too much pressure on the eyes, damaging the optic nerve and irreversible loss of vision.

What is Brimonidine?
Brimonidine belongs to a class of drugs called alpha receptor agonists, and acts to reduce the amount of fluid in the eye.

Alpha receptor agonists are substances that have similar or identical effects to adrenaline. It is also well known as a sympathetic drug, which means it mimics the sympathetic nervous system.

The sympathetic nervous system is a part of the autonomic nervous system and is responsible for the following unconscious functions.

Pupil dilation
Reduced saliva production
Heart rate increase
Suppression of the digestive system
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Use of brimonidine eye drops

Brimonidine is provided as an ophthalmic eye drop. For adults and elderly patients, the recommended dosage is to drop one drop into the affected eye twice a day, and the interval of use is about 12 hours.

Instructions for use and recommendations
Do not use this drug if the lid sealant is broken. And it is very important to wash your hands thoroughly before opening the lid.

First, turn your head back and look at the ceiling.
Then gently pull the lower eyelid down.
Place the eye drops upside down and hold tight until a drop falls into your eyes.
After that, close your eyes.
To avoid optimal use and possible systemic absorption, experts say it is good to drop this drop and press the tear bag for 1 minute. In addition, if the patient uses more than one ophthalmic drug, each drug should be administered separately at 15 minute intervals.
Once the eye drops are opened, they should be used within 28 days.
Side effects of brimonidine eye drops
The most common side effects are:

Dry mouth
Eye redness
Eye burn and itching
headache
drowsiness
However, this is generally not a serious side effect, such as the need to stop using brimonidine eye drops, but it is a temporary side effect.

Some rare side effects are:

Eye fatigue
Light fear or sensitivity to light
Swollen eyelids
lethargy
Rarely, but may cause heart palpitations or arrhythmia

Headache and light sensitivity are some of the possible side effects of the drug.

However, if you have any of the following symptoms, you should see a doctor right away.

rash
Difficulty breathing
faint
dizziness
nausea
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When brimonidine cannot be used
Treatment with brimonidine is prohibited in the following cases:

Hypersensitivity to active substances or other additives
Babies and children under 2 years
Patients treated with monoamine oxidase inhibitors (MAOI) antidepressants
Patients treated with antidepressants that affect noradrenaline transmission (eg tricyclic antidepressants)
Can you use Brimonidine during pregnancy?
Some animal studies have shown that brimonidine does not cause malformations. However, studies in rabbits showed that post-natal growth decreased after higher levels of brimonidine were found when treated in humans.

The safety of this drug during pregnancy has not been established yet, but it is better not to use brimonidine during pregnancy.

Health professionals will only consider this when the mother's potential benefits justify the potential risk to the fetus. In addition, this drug should not be used during breastfeeding.

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